Trichostatin A ameliorates Alzheimer’s disease-related pathology and cognitive deficits by increasing albumin expression and Aβ clearance in APP/PS1 mice

BACKGROUND: Alzheimer’s disease (AD) is an intractable neurodegenerative disorder in the elderly population, currently lacking a cure. Trichostatin A (TSA), a histone deacetylase inhibitor, showed some neuroprotective roles, but its pathology-improvement effects in AD are still uncertain, and the un...

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Detalles Bibliográficos
Autores principales: Su, Qiang, Li, Tian, He, Pei-Feng, Lu, Xue-Chun, Yu, Qi, Gao, Qi-Chao, Wang, Zhao-Jun, Wu, Mei-Na, Yang, Dan, Qi, Jin-Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784383/
https://www.ncbi.nlm.nih.gov/pubmed/33397436
http://dx.doi.org/10.1186/s13195-020-00746-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784383/
https://www.ncbi.nlm.nih.gov/pubmed/33397436
http://dx.doi.org/10.1186/s13195-020-00746-8

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