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Recurrent SPECC1L–NTRK fusions in pediatric sarcoma and brain tumors

The identification of rearrangements driving expression of neurotrophic receptor tyrosine kinase (NTRK) family kinases in tumors has become critically important because of the availability of effective, specific inhibitor drugs. Whole-genome sequencing (WGS) combined with RNA sequencing (RNA-seq) ca...

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Detalles Bibliográficos
Autores principales: Khuong-Quang, Dong-Anh, Brown, Lauren M., Wong, Marie, Mayoh, Chelsea, Sexton-Oates, Alexandra, Kumar, Amit, Pinese, Mark, Nagabushan, Sumanth, Lau, Loretta, Ludlow, Louise E., Gifford, Andrew J., Rodriguez, Michael, Desai, Jayesh, Fox, Stephen B., Haber, Michelle, Ziegler, David S., Hansford, Jordan R., Marshall, Glenn M., Cowley, Mark J., Ekert, Paul G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784491/
https://www.ncbi.nlm.nih.gov/pubmed/33144287
http://dx.doi.org/10.1101/mcs.a005710