Cargando…
Recurrent SPECC1L–NTRK fusions in pediatric sarcoma and brain tumors
The identification of rearrangements driving expression of neurotrophic receptor tyrosine kinase (NTRK) family kinases in tumors has become critically important because of the availability of effective, specific inhibitor drugs. Whole-genome sequencing (WGS) combined with RNA sequencing (RNA-seq) ca...
Autores principales: | Khuong-Quang, Dong-Anh, Brown, Lauren M., Wong, Marie, Mayoh, Chelsea, Sexton-Oates, Alexandra, Kumar, Amit, Pinese, Mark, Nagabushan, Sumanth, Lau, Loretta, Ludlow, Louise E., Gifford, Andrew J., Rodriguez, Michael, Desai, Jayesh, Fox, Stephen B., Haber, Michelle, Ziegler, David S., Hansford, Jordan R., Marshall, Glenn M., Cowley, Mark J., Ekert, Paul G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784491/ https://www.ncbi.nlm.nih.gov/pubmed/33144287 http://dx.doi.org/10.1101/mcs.a005710 |
Ejemplares similares
-
Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma
por: Ziegler, David S., et al.
Publicado: (2018) -
Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes
por: Ajuyah, Pamela, et al.
Publicado: (2023) -
Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor
por: Nagabushan, Sumanth, et al.
Publicado: (2021) -
DIPG-75. PRECISION MEDICINE FOR PAEDIATRIC HIGH-GRADE DIFFUSE MIDLINE GLIOMAS - RESULTS FROM THE ZERO CHILDHOOD CANCER COMPREHENSIVE PRECISION MEDICINE PROGRAM
por: Khuong-Quang, Dong-Anh, et al.
Publicado: (2020) -
Advances in CAR T cell immunotherapy for paediatric brain tumours
por: Rao, Padmashree, et al.
Publicado: (2022)