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Generation of Mesenchymal Stromal Cells with Low Immunogenicity from Human PBMC-Derived β2 Microglobulin Knockout Induced Pluripotent Stem Cells

Mesenchymal stromal cells (MSCs) are viewed as immune-privileged cells and have been broadly applied in allogeneic adoptive cell transfer for regenerative medicine or immune-suppressing purpose. However, the surface expression of human leukocyte antigen (HLA) class I molecules on MSCs could still po...

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Detalles Bibliográficos
Autores principales: Zha, Shijun, Tay, Johan Chin-Kang, Zhu, Sumin, Li, Zhendong, Du, Zhicheng, Wang, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784598/
https://www.ncbi.nlm.nih.gov/pubmed/33172291
http://dx.doi.org/10.1177/0963689720965529