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Phase II Trial of Adjuvant Dendritic Cell Vaccine in Combination with Celecoxib, Interferon-α, and Rintatolimod in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Metastases

BACKGROUND: Peritoneal metastases portend poor prognosis in the setting of standard chemotherapy. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) improves outcomes, but relapse is common. We report a phase II trial evaluating the safety and efficacy of adjuvant αDC1 v...

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Detalles Bibliográficos
Autores principales: Ramanathan, Rajesh, Choudry, Haroon, Jones, Heather, Girgis, Mark, Gooding, William, Kalinski, Pawel, Bartlett, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784622/
https://www.ncbi.nlm.nih.gov/pubmed/33400000
http://dx.doi.org/10.1245/s10434-020-09464-9