In silico docking and comparative ADMET profile of different glycogen synthase kinase 3 beta inhibitors as the potential leads for the development of anti-Alzheimer drug therapy

Glycogen synthase kinase 3 beta (GSK3 β) plays a key role in pathologic hyper phosphorylation of tau and plays an important role in the pathogenesis of Alzheimer's disease. In the present study, we have screened a set of potential hits in in silico platform to gain insight regarding binding pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Prajapat, Manisha, Sarma, Phulen, Shekhar, Nishant, Kaur, Hardeep, Singh, Sanjay, Kumar, Subodh, Kaur, Harpinder, Mahendiratta, Saniya, Sharma, Amit Raj, Kaur, Sukhmandeep, Mahalmani, Vidya M., Medhi, Bikash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784934/
https://www.ncbi.nlm.nih.gov/pubmed/33425704
http://dx.doi.org/10.4103/japtr.JAPTR_178_19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784934/
https://www.ncbi.nlm.nih.gov/pubmed/33425704
http://dx.doi.org/10.4103/japtr.JAPTR_178_19

Ejemplares similares