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In silico docking and comparative ADMET profile of different glycogen synthase kinase 3 beta inhibitors as the potential leads for the development of anti-Alzheimer drug therapy
Glycogen synthase kinase 3 beta (GSK3 β) plays a key role in pathologic hyper phosphorylation of tau and plays an important role in the pathogenesis of Alzheimer's disease. In the present study, we have screened a set of potential hits in in silico platform to gain insight regarding binding pro...
Autores principales: | Prajapat, Manisha, Sarma, Phulen, Shekhar, Nishant, Kaur, Hardeep, Singh, Sanjay, Kumar, Subodh, Kaur, Harpinder, Mahendiratta, Saniya, Sharma, Amit Raj, Kaur, Sukhmandeep, Mahalmani, Vidya M., Medhi, Bikash |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784934/ https://www.ncbi.nlm.nih.gov/pubmed/33425704 http://dx.doi.org/10.4103/japtr.JAPTR_178_19 |
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