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Effects of ketoisocaproic acid and inflammation on glucose transport in muscle cells

Branched‐chain amino acids (BCAAs) are regulators of protein metabolism. However, elevated levels of BCAAs and their metabolites are linked to insulin resistance. We previously demonstrated that the leucine metabolite, α‐ketoisocaproate (KIC), inhibited insulin‐stimulated glucose transport in myotub...

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Detalles Bibliográficos
Autores principales: Mann, Gagandeep, Adegoke, Olasunkanmi A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785050/
https://www.ncbi.nlm.nih.gov/pubmed/33400857
http://dx.doi.org/10.14814/phy2.14673