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Reprogramming of aerobic glycolysis in non‐transformed mouse liver with pyruvate dehydrogenase complex deficiency

The Pyruvate Dehydrogenase Complex (PDC), a key enzyme in glucose metabolism, catalyzes an irreversible oxidative decarboxylation reaction of pyruvate to acetyl‐CoA, linking the cytosolic glycolytic pathway to mitochondrial tricarboxylic acid cycle and oxidative phosphorylation. Earlier we reported...

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Detalles Bibliográficos
Autores principales: Patel, Mulchand S., Mahmood, Saleh, Jung, Jiwon, Rideout, Todd C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785054/
https://www.ncbi.nlm.nih.gov/pubmed/33400855
http://dx.doi.org/10.14814/phy2.14684