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Reprogramming of aerobic glycolysis in non‐transformed mouse liver with pyruvate dehydrogenase complex deficiency
The Pyruvate Dehydrogenase Complex (PDC), a key enzyme in glucose metabolism, catalyzes an irreversible oxidative decarboxylation reaction of pyruvate to acetyl‐CoA, linking the cytosolic glycolytic pathway to mitochondrial tricarboxylic acid cycle and oxidative phosphorylation. Earlier we reported...
Autores principales: | Patel, Mulchand S., Mahmood, Saleh, Jung, Jiwon, Rideout, Todd C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785054/ https://www.ncbi.nlm.nih.gov/pubmed/33400855 http://dx.doi.org/10.14814/phy2.14684 |
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