Cargando…
Point and interval estimation in two-stage adaptive designs with time to event data and biomarker-driven subpopulation selection
In personalized medicine, it is often desired to determine if all patients or only a subset of them benefit from a treatment. We consider estimation in two-stage adaptive designs that in stage 1 recruit patients from the full population. In stage 2, patient recruitment is restricted to the part of t...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785132/ https://www.ncbi.nlm.nih.gov/pubmed/32363603 http://dx.doi.org/10.1002/sim.8557 |