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CD8(low) T cells expanded following acute Trypanosoma cruzi infection and benznidazole treatment are a relevant subset of IFN-γ producers

CD8 T cells are regarded as pivotal players in both immunoprotection and immunopathology following Trypanosoma cruzi infection. Previously, we demonstrated the expansion of CD8(+) T lymphocytes in the spleen of T. cruzi-infected mice under treatment with benznidazole (N-benzyl-2-nitroimidazole aceta...

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Detalles Bibliográficos
Autores principales: Marins-Dos-Santos, Alessandro, Olivieri, Bianca Perdigão, Ferreira-Reis, Rafaella, de Meis, Juliana, Silva, Andrea Alice, de Araújo-Jorge, Tania C., Lannes-Vieira, Joseli, Cotta-de-Almeida, Vinicius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785226/
https://www.ncbi.nlm.nih.gov/pubmed/33347472
http://dx.doi.org/10.1371/journal.pntd.0008969