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Targeted Temperature Management Suppresses Hypoxia-Inducible Factor-1α and Vascular Endothelial Growth Factor Expression in a Pig Model of Cardiac Arrest

BACKGROUND: The hypoxia-inducible factor-1α (HIF-1α)/vascular endothelial growth factor (VEGF)/VEGF receptor subtype 2 (VEGFR-2) pathway has been implicated in ischemia/reperfusion injury. The aim of this study was to clarify whether whole-body hypothermic targeted temperature management (HTTM) inhi...

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Detalles Bibliográficos
Autores principales: Li, Jiebin, Li, Chunsheng, Yuan, Wei, Wu, Junyuan, Li, Jie, Li, Zhenhua, Zhao, Yongzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785329/
https://www.ncbi.nlm.nih.gov/pubmed/33403582
http://dx.doi.org/10.1007/s12028-020-01166-0