A Simple RFLP-Based Method for HFE Gene Multiplex Amplification and Determination of Hereditary Hemochromatosis-Causing Mutation C282Y and H63D Variant with Highly Sensitive Determination of Contamination

Hereditary hemochromatosis is an autosomal recessive disorder with incomplete penetrance that results from excess iron absorption and can lead to chronic liver disease, fibrosis, cirrhosis, and hepatocellular carcinoma. The most common form of hereditary hemochromatosis in Western Europe is due to a...

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Detalles Bibliográficos
Autores principales: OGOUMA-AWORET, Ludmilla, RABES, Jean-Pierre, de MAZANCOURT, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785358/
https://www.ncbi.nlm.nih.gov/pubmed/33457423
http://dx.doi.org/10.1155/2020/9396318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785358/
https://www.ncbi.nlm.nih.gov/pubmed/33457423
http://dx.doi.org/10.1155/2020/9396318

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