Establishment and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Tigecycline in Critically Ill Patients

Utilizing tigecycline-d9 as an internal standard (IS), we establish and validate a simple, effective, and rapid liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantitative measurement of tigecycline (TGC) in patient plasma. Acetonitrile was used as a precipitant to process...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Fen, Wang, Yifan, Hou, Yating, Wang, Xipei, Lan, Jinhua, Wu, Zheng, Wang, Yirong, Chen, Chunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785388/
https://www.ncbi.nlm.nih.gov/pubmed/33456470
http://dx.doi.org/10.1155/2020/6671392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785388/
https://www.ncbi.nlm.nih.gov/pubmed/33456470
http://dx.doi.org/10.1155/2020/6671392

Ejemplares similares