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Chronic Tear Deficiency Sensitizes Transient Receptor Potential Vanilloid 1-Mediated Responses in Corneal Sensory Nerves

Chronic tear deficiency enhances the excitability of corneal cold-sensitive nerves that detect ocular dryness, which can lead to discomfort in patients with dry eye disease (DED). However, changes in corneal nerve excitations through the polymodal nociceptor “transient receptor potential vanilloid 1...

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Detalles Bibliográficos
Autores principales: Masuoka, Takayoshi, Yamashita, Yuka, Nakano, Katsuya, Takechi, Kenshi, Niimura, Takahiro, Tawa, Masashi, He, Qiang, Ishizawa, Keisuke, Ishibashi, Takaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785588/
https://www.ncbi.nlm.nih.gov/pubmed/33424555
http://dx.doi.org/10.3389/fncel.2020.598678