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Maf1 Ameliorates Sepsis-Associated Encephalopathy by Suppressing the NF-kB/NLRP3 Inflammasome Signaling Pathway

BACKGROUND: The NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) inflammasome has been identified as an important mediator of blood–brain-barrier disruption in sepsis-associated encephalopathy (SAE). However, no information is available concerning the critical upstream regulators of SAE. MET...

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Detalles Bibliográficos
Autores principales: Chen, Shenglong, Tang, Chaogang, Ding, Hongguang, Wang, Zhonghua, Liu, Xinqiang, Chai, Yunfei, Jiang, Wenqiang, Han, Yongli, Zeng, Hongke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785707/
https://www.ncbi.nlm.nih.gov/pubmed/33424842
http://dx.doi.org/10.3389/fimmu.2020.594071