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Therapeutic Efficacy of a Trichinella Spiralis Paramyosin-Derived Peptide Modified With a Membrane-Targeting Signal in Mice With Antigen-Induced Arthritis

Helminth-derived molecules have the ability to modulate the host immune system. Our previous study identified a tetradecapeptide derived from Trichinella spiralis paramyosin (Ts-pmy) that could bind to human complement component C9 to inhibit its polymerization, making the peptide a candidate therap...

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Detalles Bibliográficos
Autores principales: Chen, Yi, Shao, Shuai, Huang, Jingjing, Gu, Yuan, Cheng, Yuli, Zhu, Xinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785802/
https://www.ncbi.nlm.nih.gov/pubmed/33424810
http://dx.doi.org/10.3389/fmicb.2020.608380