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Dysregulation of Neuronal Calcium Signaling via Store-Operated Channels in Huntington's Disease
Huntington's disease (HD) is a progressive neurodegenerative disorder that is characterized by motor, cognitive, and psychiatric problems. It is caused by a polyglutamine expansion in the huntingtin protein that leads to striatal degeneration via the transcriptional dysregulation of several gen...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785827/ https://www.ncbi.nlm.nih.gov/pubmed/33425919 http://dx.doi.org/10.3389/fcell.2020.611735 |