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Dysregulation of Neuronal Calcium Signaling via Store-Operated Channels in Huntington's Disease

Huntington's disease (HD) is a progressive neurodegenerative disorder that is characterized by motor, cognitive, and psychiatric problems. It is caused by a polyglutamine expansion in the huntingtin protein that leads to striatal degeneration via the transcriptional dysregulation of several gen...

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Detalles Bibliográficos
Autor principal: Czeredys, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785827/
https://www.ncbi.nlm.nih.gov/pubmed/33425919
http://dx.doi.org/10.3389/fcell.2020.611735