Mitochondrial Calcium Uniporter Deficiency in Zebrafish Causes Cardiomyopathy With Arrhythmia

Mitochondrial Ca(2 +) uptake influences energy production, cell survival, and Ca(2 +) signaling. The mitochondrial calcium uniporter, MCU, is the primary route for uptake of Ca(2 +) into the mitochondrial matrix. We have generated a zebrafish MCU mutant that survives to adulthood and exhibits dramat...

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Detalles Bibliográficos
Autores principales: Langenbacher, Adam D., Shimizu, Hirohito, Hsu, Welkin, Zhao, Yali, Borges, Alexandria, Koehler, Carla, Chen, Jau-Nian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785991/
https://www.ncbi.nlm.nih.gov/pubmed/33424641
http://dx.doi.org/10.3389/fphys.2020.617492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785991/
https://www.ncbi.nlm.nih.gov/pubmed/33424641
http://dx.doi.org/10.3389/fphys.2020.617492

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