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qPCR and qRT-PCR analysis: Regulatory points to consider when conducting biodistribution and vector shedding studies

Gene and cell therapy fields have experienced remarkable growth during the past decade. Demands for preclinical and clinical safety assessments of these cell and gene therapy test articles (TAs) have effectively increased the necessity for regulated biodistribution, vector shedding, gene expression,...

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Detalles Bibliográficos
Autores principales: Ma, Haiyan, Bell, Kristin N., Loker, Rossi N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786041/
https://www.ncbi.nlm.nih.gov/pubmed/33473355
http://dx.doi.org/10.1016/j.omtm.2020.11.007