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Vaccine-Induced CD8(+) T Cell Responses in Children: A Review of Age-Specific Molecular Determinants Contributing to Antigen Cross-Presentation

Infections are most common and most severe at the extremes of age, the young and the elderly. Vaccination can be a key approach to enhance immunogenicity and protection against pathogens in these vulnerable populations, who have a functionally distinct immune system compared to other age groups. Mor...

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Detalles Bibliográficos
Autores principales: Beijnen, Elisabeth M. S., van Haren, Simon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786054/
https://www.ncbi.nlm.nih.gov/pubmed/33424857
http://dx.doi.org/10.3389/fimmu.2020.607977