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Establishment and Characterization of a Topotecan Resistant Non-small Cell Lung Cancer NCI-H460/TPT10 Cell Line

While topotecan (TPT) is a first- and second-line chemotherapeutic drug in treating lung cancer, the development of drug resistance in tumors still reserves as a major obstacle to chemotherapeutic success. Therefore, a better understanding of the mechanisms of topotecan resistance is critical. In th...

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Detalles Bibliográficos
Autores principales: Lei, Zi-Ning, Teng, Qiu-Xu, Zhang, Wei, Fan, Ying-Fang, Wang, Jing-Quan, Cai, Chao-Yun, Lu, Kimberly W., Yang, Dong-Hua, Wurpel, John N. D., Chen, Zhe-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786180/
https://www.ncbi.nlm.nih.gov/pubmed/33425914
http://dx.doi.org/10.3389/fcell.2020.607275