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Impact of synthetic surfactant CHF5633 with SP‐B and SP‐C analogues on lung function and inflammation in rabbit model of acute respiratory distress syndrome

Acute respiratory distress syndrome (ARDS) is associated with diffuse inflammation, alveolar epithelial damage, and leakage of plasma proteins into the alveolar space, which together contribute to inactivation of pulmonary surfactant and respiratory failure. Exogenous surfactant delivery is therefor...

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Detalles Bibliográficos
Autores principales: Mikolka, Pavol, Curstedt, Tore, Feinstein, Riccardo, Larsson, Anders, Grendar, Marian, Rising, Anna, Johansson, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786196/
https://www.ncbi.nlm.nih.gov/pubmed/33403805
http://dx.doi.org/10.14814/phy2.14700