Combined bezafibrate, medroxyprogesterone acetate and valproic acid treatment inhibits osteosarcoma cell growth without adversely affecting normal mesenchymal stem cells

Drug repurposing is a cost-effective means of targeting new therapies for cancer. We have examined the effects of the repurposed drugs, bezafibrate, medroxyprogesterone acetate and valproic acid on human osteosarcoma cells, i.e., SAOS2 and MG63 compared with their normal cell counterparts, i.e. mese...

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Detalles Bibliográficos
Autores principales: Sheard, Jonathan J., Southam, Andrew D., MacKay, Hannah L., Ellington, Max A., Snow, Martyn D., Khanim, Farhat L., Bunce, Christopher M., Johnson, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786328/
https://www.ncbi.nlm.nih.gov/pubmed/33289496
http://dx.doi.org/10.1042/BSR20202505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786328/
https://www.ncbi.nlm.nih.gov/pubmed/33289496
http://dx.doi.org/10.1042/BSR20202505

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