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An Integrated Network, RNA Sequencing, and Experiment Pharmacology Approach Reveals the Active Component, Potential Target, and Mechanism of Gelsemium elegans in the Treatment of Colorectal Cancer

In this study, a combination of network pharmacology, bioinformatics analysis, molecular docking and transcriptomics was used to investigate the active ingredient and potential target of Gelsemium elegans in the treatment of colorectal cancer. Koumine was screened as the active component by targetin...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Xu, Hai-li, Liang, Jing-wei, Ding, Ying-ying, Meng, Fan-hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786369/
https://www.ncbi.nlm.nih.gov/pubmed/33425771
http://dx.doi.org/10.3389/fonc.2020.616628