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Cleavable Cross-Linkers and Mass Spectrometry for the Ultimate Task of Profiling Protein–Protein Interaction Networks in Vivo

[Image: see text] Cross-linking mass spectrometry (XL-MS) has matured into a potent tool to identify protein–protein interactions or to uncover protein structures in living cells, tissues, or organelles. The unique ability to investigate the interplay of proteins within their native environment deli...

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Detalles Bibliográficos
Autores principales: Matzinger, Manuel, Mechtler, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786381/
https://www.ncbi.nlm.nih.gov/pubmed/33151691
http://dx.doi.org/10.1021/acs.jproteome.0c00583