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Mild Acid Elution and MHC Immunoaffinity Chromatography Reveal Similar Albeit Not Identical Profiles of the HLA Class I Immunopeptidome

[Image: see text] To understand and treat immunology-related diseases, a comprehensive, unbiased characterization of major histocompatibility complex (MHC) peptide ligands is of key importance. Preceding the analysis by mass spectrometry, MHC class I peptide ligands are typically isolated by MHC imm...

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Detalles Bibliográficos
Autores principales: Sturm, Theo, Sautter, Benedikt, Wörner, Tobias P., Stevanović, Stefan, Rammensee, Hans-Georg, Planz, Oliver, Heck, Albert J. R., Aebersold, Ruedi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786382/
https://www.ncbi.nlm.nih.gov/pubmed/33141586
http://dx.doi.org/10.1021/acs.jproteome.0c00386