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Mild Acid Elution and MHC Immunoaffinity Chromatography Reveal Similar Albeit Not Identical Profiles of the HLA Class I Immunopeptidome
[Image: see text] To understand and treat immunology-related diseases, a comprehensive, unbiased characterization of major histocompatibility complex (MHC) peptide ligands is of key importance. Preceding the analysis by mass spectrometry, MHC class I peptide ligands are typically isolated by MHC imm...
Autores principales: | Sturm, Theo, Sautter, Benedikt, Wörner, Tobias P., Stevanović, Stefan, Rammensee, Hans-Georg, Planz, Oliver, Heck, Albert J. R., Aebersold, Ruedi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786382/ https://www.ncbi.nlm.nih.gov/pubmed/33141586 http://dx.doi.org/10.1021/acs.jproteome.0c00386 |
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