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D-mannose ameliorates autoimmune phenotypes in mouse models of lupus

BACKGROUND: Systemic lupus erythematosus is an autoimmune disease characterized by an overproduction of autoantibodies resulting from dysregulation in multiple immune cell types. D-mannose is a C(− 2) epimer of glucose that exhibits immunoregulatory effects in models of autoimmune diseases, such as...

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Detalles Bibliográficos
Autores principales: Wang, Haiting, Teng, Xiangyu, Abboud, Georges, Li, Wei, Ye, Shuang, Morel, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786459/
https://www.ncbi.nlm.nih.gov/pubmed/33402096
http://dx.doi.org/10.1186/s12865-020-00392-7