Isoliquiritin ameliorates depression by suppressing NLRP3-mediated pyroptosis via miRNA-27a/SYK/NF-κB axis

BACKGROUND: The NLRP3-mediated pyroptosis, which could be regulated by miRNA-27a, is a key player in the development of depression. Isoliquiritin is a phenolic flavonoid compound that has been demonstrated to suppress NLRP3-mediated pyroptosis. However, it is still unknown whether isoliquiritin coul...

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Detalles Bibliográficos
Autores principales: Li, Yuanjie, Song, Wen, Tong, Yue, Zhang, Xia, Zhao, Jianjun, Gao, Xiaojuan, Yong, Jingjiao, Wang, Hanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786465/
https://www.ncbi.nlm.nih.gov/pubmed/33402173
http://dx.doi.org/10.1186/s12974-020-02040-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786465/
https://www.ncbi.nlm.nih.gov/pubmed/33402173
http://dx.doi.org/10.1186/s12974-020-02040-8

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