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Isoliquiritin ameliorates depression by suppressing NLRP3-mediated pyroptosis via miRNA-27a/SYK/NF-κB axis

BACKGROUND: The NLRP3-mediated pyroptosis, which could be regulated by miRNA-27a, is a key player in the development of depression. Isoliquiritin is a phenolic flavonoid compound that has been demonstrated to suppress NLRP3-mediated pyroptosis. However, it is still unknown whether isoliquiritin coul...

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Detalles Bibliográficos
Autores principales:	Li, Yuanjie, Song, Wen, Tong, Yue, Zhang, Xia, Zhao, Jianjun, Gao, Xiaojuan, Yong, Jingjiao, Wang, Hanqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786465/ https://www.ncbi.nlm.nih.gov/pubmed/33402173 http://dx.doi.org/10.1186/s12974-020-02040-8

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