N6-methyladenosine dynamics in neurodevelopment and aging, and its potential role in Alzheimer’s disease

BACKGROUND: N6-methyladenosine (m(6)A) modification is known to impact many aspects of RNA metabolism, including mRNA stability and translation, and is highly prevalent in the brain. RESULTS: We show that m(6)A modification displays temporal and spatial dynamics during neurodevelopment and aging. Ge...

Descripción completa

Detalles Bibliográficos
Autores principales: Shafik, Andrew M., Zhang, Feiran, Guo, Zhenxing, Dai, Qing, Pajdzik, Kinga, Li, Yangping, Kang, Yunhee, Yao, Bing, Wu, Hao, He, Chuan, Allen, Emily G., Duan, Ranhui, Jin, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786910/
https://www.ncbi.nlm.nih.gov/pubmed/33402207
http://dx.doi.org/10.1186/s13059-020-02249-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786910/
https://www.ncbi.nlm.nih.gov/pubmed/33402207
http://dx.doi.org/10.1186/s13059-020-02249-z

Ejemplares similares