P2X7R-mediated autophagic impairment contributes to central sensitization in a chronic migraine model with recurrent nitroglycerin stimulation in mice

BACKGROUND: Central sensitization is an important pathophysiological mechanism of chronic migraine (CM). According to our previous studies, microglial activation and subsequent inflammation in the trigeminal nucleus caudalis (TNC) contribute to the central sensitization. The P2X7 receptor (P2X7R) is...

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Detalles Bibliográficos
Autores principales: Jiang, Li, Zhang, Yixin, Jing, Feng, Long, Ting, Qin, Guangcheng, Zhang, Dunke, Chen, Lixue, Zhou, Jiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786980/
https://www.ncbi.nlm.nih.gov/pubmed/33402188
http://dx.doi.org/10.1186/s12974-020-02056-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786980/
https://www.ncbi.nlm.nih.gov/pubmed/33402188
http://dx.doi.org/10.1186/s12974-020-02056-0

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