Inhibition of Cathepsin S Induces Mitochondrial Apoptosis in Glioblastoma Cell Lines Through Mitochondrial Stress and Autophagosome Accumulation

Cathepsin S (CTSS), a lysosomal cysteine protease, is overexpressed in various cancers, including glioblastoma (GB). A high level of CTSS is associated with tumor progression and poor outcome in GB. However, the underlying mechanisms of its role in the biological characteristics of G5B remain to be...

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Detalles Bibliográficos
Autores principales: Fei, Maoxing, Zhang, Li, Wang, Handong, Zhu, Yihao, Niu, Wenhao, Tang, Ting, Han, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787074/
https://www.ncbi.nlm.nih.gov/pubmed/33425712
http://dx.doi.org/10.3389/fonc.2020.516746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787074/
https://www.ncbi.nlm.nih.gov/pubmed/33425712
http://dx.doi.org/10.3389/fonc.2020.516746

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