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The protective effects of phosphodiesterase-5 inhibitor, sildenafil on post-resuscitation cardiac dysfunction of cardiac arrest: by regulating the miR-155-5p and miR-145-5p

BACKGROUND: MiRNA-155 and miRNA-145 have been demonstrated to function as a key regulator in the development of the cardiovascular system. Recent experimental and clinical studies have indicated the cardioprotective role of sildenafil during ischemia/reperfusion (I/R) injury. This study was designed...

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Detalles Bibliográficos
Autores principales: He, Yong, Wang, Guoxing, Li, Chuang, Wang, Yuxing, Zhang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787123/
https://www.ncbi.nlm.nih.gov/pubmed/33407761
http://dx.doi.org/10.1186/s13049-020-00819-5