A genome-wide strategy to identify causes and consequences of retrotransposon expression finds activation by BRCA1 in ovarian cancer

It is challenging to identify the causes and consequences of retrotransposon expression in human disease due to the hundreds of active genomic copies and their poor conservation across species. We profiled genomic insertions of retrotransposons in ovarian cancer. In addition, in ovarian and breast c...

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Detalles Bibliográficos
Autores principales: Alkailani, Maisa, Palidwor, Gareth, Poulin, Ariane, Mohan, Raghav, Pepin, David, Vanderhyden, Barbara, Gibbings, Derrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Cancer Gene Regulation, Chromatin, and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787265/
https://www.ncbi.nlm.nih.gov/pubmed/33447827
http://dx.doi.org/10.1093/narcan/zcaa040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787265/
https://www.ncbi.nlm.nih.gov/pubmed/33447827
http://dx.doi.org/10.1093/narcan/zcaa040

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