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A genome-wide strategy to identify causes and consequences of retrotransposon expression finds activation by BRCA1 in ovarian cancer
It is challenging to identify the causes and consequences of retrotransposon expression in human disease due to the hundreds of active genomic copies and their poor conservation across species. We profiled genomic insertions of retrotransposons in ovarian cancer. In addition, in ovarian and breast c...
Autores principales: | Alkailani, Maisa, Palidwor, Gareth, Poulin, Ariane, Mohan, Raghav, Pepin, David, Vanderhyden, Barbara, Gibbings, Derrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787265/ https://www.ncbi.nlm.nih.gov/pubmed/33447827 http://dx.doi.org/10.1093/narcan/zcaa040 |
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