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MAFG is a potential therapeutic target to restore chemosensitivity in cisplatin-resistant cancer cells by increasing reactive oxygen species

Adjuvant chemotherapy for solid tumors based on platinum-derived compounds such as cisplatin is the treatment of choice in most cases. Cisplatin triggers signaling pathways that lead to cell death, but it also induces changes in tumor cells that modify the therapeutic response, thereby leading to ci...

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Detalles Bibliográficos
Autores principales: VERA-PUENTE, OLGA, RODRIGUEZ-ANTOLIN, CARLOS, SALGADO-FIGUEROA, ANA, MICHALSKA, PATRYCJA, PERNIA, OLGA, REID, BRETT M., ROSAS, ROCÍO, GARCIA-GUEDE, ALVARO, SACRISTÁN, SILVIA, JIMENEZ, JULIA, ESTEBAN-RODRIGUEZ, ISABEL, MARTIN, M. ELENA, SELLERS, THOMAS A., LEÓN, RAFAEL, GONZALEZ, VÍCTOR M., DE CASTRO, JAVIER, DE CACERES, INMACULADA IBANEZ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787305/
https://www.ncbi.nlm.nih.gov/pubmed/30053382
http://dx.doi.org/10.1016/j.trsl.2018.06.005