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Rapid discovery of novel prophages using biological feature engineering and machine learning

Prophages are phages that are integrated into bacterial genomes and which are key to understanding many aspects of bacterial biology. Their extreme diversity means they are challenging to detect using sequence similarity, yet this remains the paradigm and thus many phages remain unidentified. We pre...

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Detalles Bibliográficos
Autores principales: Sirén, Kimmo, Millard, Andrew, Petersen, Bent, Gilbert, M Thomas P, Clokie, Martha R J, Sicheritz-Pontén, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787355/
https://www.ncbi.nlm.nih.gov/pubmed/33575651
http://dx.doi.org/10.1093/nargab/lqaa109