Insulin receptor substrate in brain-enriched exosomes in subjects with major depression: on the path of creation of biosignatures of central insulin resistance

Insulin signaling is critical for neuroplasticity, cerebral metabolism as well as for systemic energy metabolism. In rodent studies impaired brain insulin signaling with resultant insulin resistance (IR) modulates synaptic plasticity and the corresponding behavioral functions. Despite discoveries of...

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Detalles Bibliográficos
Autores principales: Nasca, Carla, Dobbin, Josh, Bigio, Benedetta, Watson, Kathleen, de Angelis, Paolo, Kautz, Marin, Cochran, Ashly, Mathé, Aleksander A, Kocsis, James H, Lee, Francis S, Murrough, James W, McEwen, Bruce S, Rasgon, Natalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787430/
https://www.ncbi.nlm.nih.gov/pubmed/32536688
http://dx.doi.org/10.1038/s41380-020-0804-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787430/
https://www.ncbi.nlm.nih.gov/pubmed/32536688
http://dx.doi.org/10.1038/s41380-020-0804-7

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