Cross-linking of T cell to B cell lymphoma by the T cell bispecific antibody CD20-TCB induces IFNγ/CXCL10-dependent peripheral T cell recruitment in humanized murine model

Diffuse large B cell lymphomas (DLBCL) are a highly heterogeneous subtype of Non Hodgkin Lymphoma (NHL), accounting for about 25% of NHL. Despite an increased progression-free survival upon therapy, 40–50% of patients develop relapse/refractory disease, therefore there remains an important medical n...

Descripción completa

Detalles Bibliográficos
Autores principales: Cremasco, Floriana, Menietti, Elena, Speziale, Dario, Sam, Johannes, Sammicheli, Stefano, Richard, Marine, Varol, Ahmet, Klein, Christian, Umana, Pablo, Bacac, Marina, Colombetti, Sara, Perro, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787458/
https://www.ncbi.nlm.nih.gov/pubmed/33406104
http://dx.doi.org/10.1371/journal.pone.0241091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787458/
https://www.ncbi.nlm.nih.gov/pubmed/33406104
http://dx.doi.org/10.1371/journal.pone.0241091

Ejemplares similares