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Characterization of cerebrospinal fluid (CSF) microbiota from patients with CSF shunt infection and reinfection using high throughput sequencing of 16S ribosomal RNAgenes

BACKGROUND: Nearly 20% of patients with cerebrospinal fluid (CSF) shunt infection develop reinfection. It is unclear whether reinfections are caused by an organism previously present or are independent infection events. OBJECTIVE: We used bacterial culture and high throughput sequencing (HTS) of 16S...

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Detalles Bibliográficos
Autores principales: Whitlock, Kathryn B., Pope, Christopher E., Hodor, Paul, Hoffman, Lucas R., Limbrick, David L., McDonald, Patrick J., Hauptman, Jason S., Ojemann, Jeffrey G., Simon, Tamara D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787469/
https://www.ncbi.nlm.nih.gov/pubmed/33406142
http://dx.doi.org/10.1371/journal.pone.0244643