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Polarization-sensitive stimulated Raman scattering imaging resolves amphotericin B orientation in Candida membrane
Ergosterol-targeting amphotericin B (AmB) is the first line of defense for life-threatening fungal infections. Two models have been proposed to illustrate AmB assembly in the cell membrane; one is the classical ion channel model in which AmB vertically forms transmembrane tunnel and the other is a r...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787481/ https://www.ncbi.nlm.nih.gov/pubmed/33523971 http://dx.doi.org/10.1126/sciadv.abd5230 |