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Testing SARS-CoV-2 vaccine efficacy through deliberate natural viral exposure

BACKGROUND: A vaccine trial with a conventional challenge design can be very fast once it starts, but it requires a long prior process, in part to grow and standardize challenge virus in the laboratory. This detracts somewhat from its overall promise for accelerated efficacy testing of severe acute...

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Detalles Bibliográficos
Autores principales: Eyal, Nir, Lipsitch, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787506/
https://www.ncbi.nlm.nih.gov/pubmed/33421580
http://dx.doi.org/10.1016/j.cmi.2020.12.032