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Global metabolomic and lipidomic analysis reveals the potential mechanisms of hemolysis effect of Ophiopogonin D and Ophiopogonin D' in vivo

BACKGROUND: OPD and OPD' are the two main active components of Ophiopogon japonicas in Shenmai injection (SMI). Being isomers of each other, they are supposed to have similar pharmacological activities, but the actual situation is complicated. The difference of hemolytic behavior between OPD an...

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Detalles Bibliográficos
Autores principales: Xu, Huan-Hua, Jiang, Zhen-Hong, Huang, Cong-Shu, Sun, Yu-Ting, Xu, Long-Long, Tang, Xiang-Ling, Tan, Hong-Ling, Ma, Zeng-Chun, Gao, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787624/
https://www.ncbi.nlm.nih.gov/pubmed/33407692
http://dx.doi.org/10.1186/s13020-020-00412-z