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Protective cellular and mucosal immune responses following nasal administration of a whole gamma-irradiated influenza A (subtype H1N1) vaccine adjuvanted with interleukin-28B in a mouse model

The use of gamma-irradiated influenza A virus (γ-Flu), retains most of the viral structural antigens, represent a promising option for vaccine development. However, despite the high effectiveness of γ-Flu vaccines, the need to incorporate an adjuvant to improve vaccine-mediated protection seems inev...

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Detalles Bibliográficos
Autores principales: Sabbaghi, Ailar, Zargar, Mohsen, Zolfaghari, Mohammad Reza, Motamedi-Sedeh, Farahnaz, Ghaemi, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787640/
https://www.ncbi.nlm.nih.gov/pubmed/33409549
http://dx.doi.org/10.1007/s00705-020-04900-3