Simultaneous Determination of Ropivacaine and 3-Hydroxy Ropivacaine in Cerebrospinal Fluid by UPLC-MS/MS

In this paper, a UPLC-MS/MS method was developed for the determination of ropivacaine and its metabolite 3-hydroxy ropivacaine in cerebrospinal fluid. The cerebrospinal fluid was processed by ethyl acetate liquid-liquid extraction. The multiple reaction monitoring (MRM) mode was used for quantitativ...

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Detalles Bibliográficos
Autores principales: Chen, Siyuan, Ma, Jianshe, Wang, Xianqin, Zhou, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787762/
https://www.ncbi.nlm.nih.gov/pubmed/33490261
http://dx.doi.org/10.1155/2020/8844866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787762/
https://www.ncbi.nlm.nih.gov/pubmed/33490261
http://dx.doi.org/10.1155/2020/8844866

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