Involvement of the miR-137-3p/CAPN-2 Interaction in Ischemia-Reperfusion-Induced Neuronal Apoptosis through Modulation of p35 Cleavage and Subsequent Caspase-8 Overactivation

BACKGROUND: Neuron survival after ischemia-reperfusion (IR) injury is the primary determinant of motor function prognosis. MicroRNA- (miR-) based gene therapy has gained attention recently. Our previous work explored the mechanisms by which miR-137-3p modulates neuronal apoptosis in both in vivo and...

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Detalles Bibliográficos
Autores principales: Wang, He, Yu, Qian, Zhang, Zai-Li, Ma, Hong, Li, Xiao-Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787780/
https://www.ncbi.nlm.nih.gov/pubmed/33456665
http://dx.doi.org/10.1155/2020/2616871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787780/
https://www.ncbi.nlm.nih.gov/pubmed/33456665
http://dx.doi.org/10.1155/2020/2616871

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