Nutrient Sensor mTOR and OGT: Orchestrators of Organelle Homeostasis in Pancreatic β-Cells

The purpose of this review is to integrate the role of nutrient-sensing pathways into β-cell organelle dysfunction prompted by nutrient excess during type 2 diabetes (T2D). T2D encompasses chronic hyperglycemia, hyperlipidemia, and inflammation, which each contribute to β-cell failure. These factors...

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Detalles Bibliográficos
Autores principales: Esch, Nicholas, Jo, Seokwon, Moore, Mackenzie, Alejandro, Emilyn U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787834/
https://www.ncbi.nlm.nih.gov/pubmed/33457426
http://dx.doi.org/10.1155/2020/8872639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787834/
https://www.ncbi.nlm.nih.gov/pubmed/33457426
http://dx.doi.org/10.1155/2020/8872639

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